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The mean squared displacement of each nanoparticle in the plane of focus of the microscope, r2(τ) [x(tτ)x(t)]2 y(tτ)y(t)2is calculated fromthe time-dependent coordinates of the nanoparticles x(t) and y(t) in the x and y directions of the plane of focus; t is the elapsed time, t is the time lag or duration of observation, and the brackets represent time averaging.

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